CCNP 28th Annual Meeting

SATURDAY JULY 2, 2005
12:00-17:00Registration (Main lobby Fairmount)
12:00-16:00CCNP Council Meeting (Health Sciences Centre, Room 2860)
16:00-17:00Public Lecture (Health Sciences Centre, Main Auditorium)
Sidney Kennedy (University Health Network, University of Toronto)
Advances in understanding and treating mood disorders.
17:30-20:00CCNP Welcoming Reception (The Court Garden, Fairmont Newfoundland Hotel)

SUNDAY JULY 3, 2005
08:00-17:00Registration (Fort Williams Prefunction Area)
08:00-08:30Continental Breakfast (Fort Williams Prefunction Area)
08:30-08:45Opening Remarks (Salon B)
Patricia Boksa, CCNP President
Nizar Ladha, Chair, Local Organizing Committee
08:45-10:45Special Plenary Symposium: Current Issues in Psychopharmacology: A Collegium Internationale Neuro-Psychopharmacologicum (CINP) Executive Perspective (Salon B)

Chair: Oakley Ray (Psychology, Pharmacology and Psychiatry, Vanderbilt University, Nashville, Tennessee)

Herb Meltzer (Psychology, Pharmacology and Psychiatry, Vanderbilt University, Nashville, Tennessee) Serotonin receptors: The key to atypical antipsychotic drug action

Brian Leonard (Pharmacology, National University of Ireland, Galway, Ireland) Inflammation, stress and depression:What do antidepressants do?
Torgny Svensson (Physiology and Pharmacology, Karolinska Instutitet, Stockholm, Sweden) Alpha2 adrenoceptor blockage in antipsychotic drug action and cognitive enhancement in schizophrenia
10:45-11:15Coffee break (Fort Williams Prefunction Area)
11:15-13:15Symposium 2: Immune mechanisms in psychiatric and neurodegenerative diseases (Salon B)

Chair: Cai Song (Biomedical Science, University Of Prince Edward Island and NRC Institute of Nutrisciences and Health, Charlottetown)

Wee Yong (Oncology and Clinical Neurosciences, University of Calgary, Calgary) Neuroinflammation in psychiatric and neurodegenerative diseases: Friend and Foe.

Norbert Müller (Psychiatry and Psychotherapy, Ludwig-Maximilans University, Munich, Germany) Therapeutic implications of immune mechanisms in psychiatric disorders.

Adrian Dunn (Pharmacology and Therapeutics, Louisiana State University, Baton Rouge, Louisiana) Proinflammatory cytokines and the function of the HPA axis: implication in psychiatric disorders

Cai Song (Biomedical Science, University Of Prince Edward Island and NRC Institute of Nutrisciences and Health, Charlottetown) The role of cytokines in depressive illness: an update.
11:15-13:15Symposium 3: Novel pharmacological approaches to dementia treatment: How rats inform the clinic (Salon C/D)

Chair: Hans Dringenberg (Psychology and Centre for Neuroscience Studies, Queen's University, Kingston)

Peter Cain (Psychology and Neuroscience, University of Western Ontario, London) Studying adaptive behaviour and spatial memory with multiple combinations of neurotransmitter antagonists as a model of Alzheimer disease

Hans Dringenberg (Psychology and Centre for Neuroscience Studies, Queen's University, Kingston) Combined monoaminergic-cholinergic enhancement for the effective restoration of cortical activation: evidence from EEG studies in rats"

James Reynolds (Pharmacology and Toxicology and Centre for Neuroscience Studies, Queen's University, Kingston) Generation and optimization of NO mimetics for the treatment of neurodegenerative disorders"

Remi Quirion (Douglas Hospital Research Centre, Psychiatry and Neurology/Neurosurgery, McGill University, Montreal) Neuroprotective effects of IGF-1 and natural products: possible relevance to the treatment for dementia"
13:15-14:45Lunch (Court Garden)
14:45-16:45Symposium 4: Cholesterol, lipid metabolism and mental health (Salon B)

Chair: Gustavo Turecki (McGill Group for Suicide Studies, McGill University, Montreal)

Frank Pfrieger (Max-Planck/CNRS Group and University of Hamburg, Hamburg, Germany) Cholesterol homeostasis and function in the CNS

Aleksandra Lalovic (McGill Group for Suicide Studies, McGill University, Montreal) Brain lipid metabolism in suicide completers

Mathew Muldoon (Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania) The potential effects of low or lowered serum cholesterol on cognitive performance

Francois Lesperance (Department of Psychiatry, University of Montreal, Montreal) Fatty acids and major depressive disorders
14:45-16:45Symposium 5: The amygdala and bed nucleus of stria terminalis: Effects of motivational and emotional factors. (Salon C/D)

Chair: Jane Stewart (Center for Studies in Behavioral Neurobiology Concordia University, Montreal).

Shimon Amir (Center for Studies in Behavioral Neurobiology Concordia University, Montreal) Subordinate circadian clocks in the amydgala and BNST are influenced by emotional and motivational events.

Jane Stewart (Center for Studies in Behavioral Neurobiology, Concordia University, Montreal) CRF and noradrenaline in the central amygdala and BNST play a role in stress induced relapse to drug seeking

Suzanne Erb (Division of Life Sciences, University of Toronto at Scarborough, Scarborough) Long-lasting effects of cocaine pre-exposure on responsiveness to CRF and footshock stress: Implications for stress-induced relapse

Eric Dumont (The Vollum Institute, Portland, Oregon) Cocaine increases excitatory synaptic transmission in the bed nucleus of the stria terminalis
16:45-17:45Heinz Lehmann Award Lecture (Salon B)
Recipient TBA Lecture
17:45-19:00Poster Session 1 (Garrison Signal Room)
See the end of the program for listing of poster presenters. Posters will be available for the duration of the meeting. Poster presenters will be available for discussion during the specified session times.

MONDAY JULY 4, 2005
08:00-17:00Registration (Fort Williams Prefunction
Area)
08:00-8:45Breakfast (Fort Williams Prefunction Area)
08:45-10:45Symposium 6: Psychopharmacological
treatment of aggression, self-injurious behavior and
destruction/disruption in the developmentally disabled: Exploration of a parallel university (Salon B)

Chair: David Janowsky (Psychiatry, University of North Carolina, Chapel Hill, North Carolina)

George Breese (Psychiatry, University of North Carolina, Chapel Hill, North Carolina) Neurochemical and anatomical underpinnings of aggression and SIB in a rat model of mental retardation.

Chrissoula Stavrakaki (Psychiatry, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa) Treatment of aggression in developmentally disabled children and adults by mood stabilizers

Rob Nicolson(Psychiatry, University of Western Ontario, London) Use of serotonergic and other antidepressants in the treatment of aggression and SIB in the developmentally disabled.

David Janowsky (Psychiatry, University of North Carolina, Chapel Hill, North Carolina) Treatment of aggression, SIB and destruction by atypical and conventional antipsychotic agents in the autistic and the mentally retarded: efficacy and outcome, pitfalls, and special considerations.
08:45-10:45Symposium 7: Molecular mechanisms of behavioral change: Implications for psychiatric disorders (Salon C/D)

Chair: Rick Beninger (Psychology and Psychiatry, Queen's University., Kingston)

Peter Kalivas (Physiology, Medical University of South Carolina, Charleston) Molecular changes following chronic cocaine: implications for drug addiction and relapse

Sheena Josselyn (Integrative Biology Program, Hospital for Sick Children, Toronto) Molecular mechanisms involved in fear learning: implications for post-traumatic stress disorder

Elena Chartoff (McClean Hospital, Harvard Medical School, Belmont, Massachusetts) Behavioral adaptations associated with nucleus accumbens CREB activation implications for depression

Richard J. Beninger (Psychology and Psychiatry, Queen's University., Kingston) Signaling molecules in reward-related learning: implications for schizophrenia
10:45-11:15Coffee break (Fort Williams Prefunction Area)
11:15-12:15Innovation in Neuropsychopharmacology Award Lecture (Salon B)
Recipient TBA
12:15-14:00CCNP Business Meeting (Salon B)
12:15-14:00Lunch (Court Garden)
14:00-16:00Special Symposium: CCNP The Next Generation (Salon B)
TBA Speakers to be selected from the abstracts submitted by trainees. (6 speakers @ 15 min+5 min discussion)
16:10-17:00Memorial University's John Williams Lectureship (Salon B) Michael Meaney (Program for the Study of Behavior, Genes and Environment, McGill University) Early life events and vulnerability to chronic illness, including depression, anxiety disorders, schizophrenia and drug abuse
17:00-17:30John Williams Lectureship Reception (Court Garden)
17:30-19:00Poster Session 2 (Garrison Signal Room) See the end of the program for listing of poster presenters.
19:00Banquet (Salon B Fairmount Newfoundland Hotel)

TUESDAY JULY 5, 2005
08:00-11:00Registration (Fort Williams Prefunction Area)
08:00-8:30Breakfast (Fort Williams Prefunction Area)
08:30-09:30Young Investigator Award Lecture (Salon B) Recipient TBA
09:30-10:30Plenary Lecture (Salon B) Anthony Grace (University of Pittsburgh) A hypothesis for the etiology of schizophrenia
10:30-11:00Coffee Break (Fort Williams Prefunction Area)
11:00-13:00Symposium 8: Imaging studies of the serotonergic system in affective disorders (Salon B)

Chair: Mirko Diksic (Neurology/Neurosurgery, McGill University, Montreal)

John Mann (New York State Psychiatric Institute and Columbia University, New York, New York) PET studies of mood disorders: Effects of genes and environment on the serotonin system

Jeffrey Meyer (Centre for Addiction and Mental Health, Toronto) Brain serotonin 2 receptors, and the serotonin transporter during depression in vivo: Relationship to dysfunctional attitudes

Hideo Tsukada (Central Research Laboratory, Hamamatsu Photonics K.K., Hamakita, Shizuoka, Japan) Animal PET research for functional imaging of the serotonergic neuronal system

Mirko Diksic (Neurology/Neurosurgery, McGill University, Montreal) Serotonin synthesis and its modulation with drugs
13:00-13:15Concluding Remarks (Salon B) Patricia Boksa, CCNP President Nizar Ladha, Chair, Local Organizing Committee